LDB3 Rabbit Polyclonal Antibody (CAB7462)
- SKU:
- CAB7462
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | LDB3 Rabbit Polyclonal Antibody |
SKU: | CAB7462 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human LDB3 (NP_001073585.1). |
Sequence: | MSYS VTLT GPGP WGFR LQGG KDFN MPLT ISRI TPGS KAAQ SQLS QGDL VVAI DGVN TDTM THLE AQNK IKSA SYNL SLTL QKSK RPIP ISTT APPV QTPL PVIP HQKV VVNS PANA DYQE RFNP SALK DSAL STHK PIEV KGLG GKAT IIHA QYNT PISM YSQD AIMD AIAG QAQA QGSD FSGS LPIK DLAV DSAS PVYQ AVIK SQNK PEDE ADEW ARRS SNLQ SRSF RILA QMTG TEFM QDPD EEAL RRSR ERFE TERN SPRF AKLR NWHH GLSA QILN VKS |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | MFM4; ZASP; CMD1C; CMH24; CMPD3; LVNC3; CYPHER; LDB3Z1; LDB3Z4; ORACLE; PDLIM6; LDB3 |
Positive Sample: | HL-60,MCF7,U-937,Raji,BT-474,Mouse skeletal muscle,Rat skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Cytoplasm, Z line, cytoskeleton, myofibril, perinuclear region, pseudopodium, sarcomere. |
Calculated MW: | 77kDa |
Observed MW: | 50kDa/90kDa |
This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains.
Purification Method: | Affinity purification |
Gene ID: | 11155 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |