The LDAH Antibody (PAC041342) is a potent tool for researchers studying the LDAH protein, which is involved in regulating immune responses and cell metabolism. This polyclonal antibody is raised in rabbits and has been validated for use in Western blot applications. It specifically targets the LDAH protein, allowing for accurate detection and analysis in various cell types, making it an ideal choice for studies in immunology and cancer research.LDAH, also known as Lysophospholipase D, plays a crucial role in immune system regulation and cellular metabolism.
By understanding the function of LDAH, researchers can gain insights into diseases such as cancer, autoimmune disorders, and metabolic disorders. This antibody provides a valuable tool for investigating the role of LDAH in immune modulation and disease development, ultimately contributing to the development of targeted therapies and treatments.
Western blot. All lanes: LDAH antibody at 8µg/ml. Lane 1: Hela whole cell lysate. Lane 2: Jurkat whole cell lysate. Lane 3: A431 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 38, 33, 23 kDa. Observed band size: 38 kDa.
Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO41342 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO41342 at dilution of 1:100.
Background:
Serine lipid hydrolase associated with lipid droplets. Highly expressed in macrophage-rich areas in atherosclerotic lesions, suggesting that it could promote cholesterol ester turnover in macrophages.
LDAH: Belongs to the UPF0554 family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 2p24.1Cellular Component: endoplasmic reticulum; lipid particleMolecular Function: lipase activityBiological Process: lipid catabolic process; sequestering of lipid
