LCP2 Rabbit Polyclonal Antibody (CAB2567)
- SKU:
- CAB2567
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | LCP2 Rabbit Polyclonal Antibody |
SKU: | CAB2567 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 159-533 of human LCP2 (NP_005556.1). |
Sequence: | SILP AKPF PNSN SMYI DRPP SGKT PQQP PVPP QRPM AALP PPPA GRNH SPLP PPQT NHEE PSRS RNHK TAKL PAPS IDRS TKPP LDRS LAPF DREP FTLG KKPP FSDK PSIP AGRS LGEH LPKI QKPP LPPT TERH ERSS PLPG KKPP VPKH GWGP DRRE NDED DVHQ RPLP QPAL LPMS SNTF PSRS TKPS PMNP LPSS HMPG AFSE SNSS FPQS ASLP PYFS QGPS NRPP IRAE GRNF PLPL PNKP RPPS PAEE ENSL NEEW YVSY ITRP EAEA ALRK INQD GTFL VRDS SKKT TTNP YVLM VLYK DKVY NIQI RYQK ESQV YLLG TGLR GKED FLSV SDII DYFR KMPL LLID GKNR GSRY QCTL THAA GYP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | IMD81; SLP76; SLP-76; LCP2 |
Positive Sample: | Jurkat,U-937,THP-1 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 60kDa |
Observed MW: | 76kDa |
This gene encodes an adapter protein that acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. The encoded protein associates with growth factor receptor bound protein 2, and is thought to play a role TCR-mediated intracellular signal transduction. A similar protein in mouse plays a role in normal T-cell development and activation. Mice lacking this gene show subcutaneous and intraperitoneal fetal hemorrhaging, dysfunctional platelets and impaired viability.
Purification Method: | Affinity purification |
Gene ID: | 3937 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |