The LCE3C Antibody (PACO59121) is a high-quality polyclonal antibody designed for research involving LCE3C, a member of the late cornified envelope (LCE) gene cluster. LCE proteins are involved in the formation of the cornified envelope, which is essential for maintaining the barrier function of the skin.This antibody, raised in rabbits, has been validated for use in a variety of research applications, including Western blotting and immunofluorescence. It specifically binds to the LCE3C protein, allowing for the detection and analysis of LCE3C expression in human samples.
Research into LCE proteins is crucial for understanding the molecular mechanisms underlying skin barrier function and the pathogenesis of skin disorders such as psoriasis and atopic dermatitis. The LCE3C Antibody provides researchers with a valuable tool for investigating the role of LCE3C in skin biology and disease, ultimately leading to the development of novel therapeutic strategies for skin disorders.
Antibody Name:
LCE3C Antibody (PACO59121)
Antibody SKU:
PACO59121
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:200-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Late cornified envelope protein 3C protein (1-94AA)
Immunofluorescence staining of HepG2 cells with PACO59121 at 1:33, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Precursors of the cornified envelope of the stratum corneum.
Synonyms:
Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A), LCE3C, LEP15 SPRL3A
UniProt Protein Function:
LCE3C: Precursors of the cornified envelope of the stratum corneum. Belongs to the LCE familyChromosomal Location of Human Ortholog: 1q21.3Biological Process: keratinization
late cornified envelope protein 3C; late envelope protein 15; small proline rich-like (epidermal differentiation complex) 3A; small proline-rich-like epidermal differentiation complex protein 3A
UniProt Protein Name:
Late cornified envelope protein 3C
UniProt Synonym Protein Names:
Late envelope protein 15; Small proline-rich-like epidermal differentiation complex protein 3A
