LAYN Antibody (PACO63667)
- SKU:
- PACO63667
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
LAYN Antibody (PACO63667)
The Layn Antibody (PAC06367) is a high-quality polyclonal antibody specifically designed for research involving Layn, a cell surface molecule known for its role in immune regulation and inflammation. This antibody, generated in rabbits, is highly reactive with samples from various species, including human, and has been validated for use in Western blot applications.Layn, also known as immune modulator protein, is involved in regulating immune responses and inflammatory processes. Its function in immune modulation makes it a promising target for research into various diseases, such as autoimmune disorders, cancer, and chronic inflammatory conditions.
Understanding the role of Layn is crucial for developing therapies that harness the immune system for therapeutic benefit.The Layn Antibody (PAC06367) binds specifically to Layn protein, allowing for accurate detection and analysis in different cell types, making it ideal for studies in immunology and cancer research. Researchers can rely on this antibody for precise and reliable results, aiding in the advancement of scientific knowledge and potential therapeutic interventions.
| Antibody Name: | LAYN Antibody (PACO63667) |
| Antibody SKU: | PACO63667 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Layilin protein (262-382AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of U251 cells with PACO63667 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Receptor for hyaluronate. |
| Synonyms: | Layilin, LAYN |
| UniProt Protein Function: | LAYN: Receptor for hyaluronate. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Membrane protein, integral Chromosomal Location of Human Ortholog: 11q23.1 Cellular Component: ruffle; cell surface; focal adhesion; integral to membrane Molecular Function:hyaluronic acid binding; carbohydrate binding |
| UniProt Code: | Q6UX15 |
| NCBI GenInfo Identifier: | 74738165 |
| NCBI Gene ID: | 143903 |
| NCBI Accession: | Q6UX15.1 |
| UniProt Secondary Accession: | Q6UX15,Q8TAY8, Q96NC5, Q96NF3, A6NJB0, B4DJU0, |
| UniProt Related Accession: | Q6UX15 |
| Molecular Weight: | 382 |
| NCBI Full Name: | Layilin |
| NCBI Synonym Full Names: | layilin |
| NCBI Official Symbol: | LAYNÂ Â |
| NCBI Protein Information: | layilin |
| UniProt Protein Name: | Layilin |
| Protein Family: | Layilin |
| UniProt Gene Name: | LAYNÂ Â |
| UniProt Entry Name: | LAYN_HUMAN |
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