The LAT2 Polyclonal Antibody (CAB10007) is a valuable tool for researchers studying LAT2, a key protein involved in T cell activation and immune signaling pathways. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to LAT2, this antibody enables precise detection and analysis of LAT2 expression in various cell types.LAT2, also known as Linker for Activation of T Cells 2, plays a crucial role in T cell receptor signaling and activation, making it essential for proper immune responses.
Research on LAT2 can provide insights into autoimmune diseases, allergies, and immune deficiencies, as well as potential therapeutic targets for immunomodulation. Understanding the functions and regulation of LAT2 is essential for developing strategies to manipulate immune responses in various disease contexts.
Product Name:
LAT2 Polyclonal Antibody
SKU:
CAB24043
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 201-300 of human SLC7A8 (NP_036376.2).
Enables several functions, including neutral amino acid transmembrane transporter activity; thyroid hormone transmembrane transporter activity; and toxin transmembrane transporter activity. Involved in L-alanine import across plasma membrane; L-leucine import across plasma membrane; and thyroid hormone transport. Located in plasma membrane. Part of basolateral plasma membrane and microvillus membrane.
Purification Method:
Affinity purification
Gene ID:
23428
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse testis using LAT2 Rabbit pAb(CAB24043) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.