LASP1 Rabbit Polyclonal Antibody (CAB3941)
- SKU:
- CAB3941
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | LASP1 Rabbit Polyclonal Antibody |
SKU: | CAB3941 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-205 of human LASP1 (NP_006139.1). |
Sequence: | RMGP SGGE GMEP ERRD SQDG SSYR RPLE QQQP HHIP TSAP VYQQ PQQQ PVAQ SYGG YKEP AAPV SIQR SAPG GGGK |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:1000 - 1:3000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | MLN50; Lasp-1; LASP1 |
Positive Sample: | A-549,BT-474,SKOV3,U-87MG,LO2,Mouse liver,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, cell cortex, cytoskeleton. |
Calculated MW: | 30kDa |
Observed MW: | 37kDa |
This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer.
Purification Method: | Affinity purification |
Gene ID: | 3927 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |