The LASP1 Polyclonal Antibody (CAB3941) is a valuable tool for researchers studying LASP1, a protein involved in cell migration and adhesion processes. This antibody, generated in rabbits, shows high specificity and reactivity towards LASP1 in human samples, making it ideal for Western blotting applications. By targeting LASP1, researchers can investigate its role in cancer metastasis, cell motility, and cytoskeletal dynamics.LASP1, also known as LIM and SH3 domain protein 1, is a key player in cellular processes that drive tumor progression and invasion.
Its overexpression has been linked to aggressive phenotypes in various cancer types, making it a potential therapeutic target. By studying LASP1 with this antibody, researchers can uncover new insights into cancer biology and potentially develop targeted therapies to inhibit its function in cancer cells.Overall, the LASP1 Polyclonal Antibody (CAB3941) offers a reliable tool for investigating the role of LASP1 in cancer biology and cell motility processes, providing valuable information for potential therapeutic strategies targeting this protein.
Product Name:
LASP1 Rabbit Polyclonal Antibody
SKU:
CAB3941
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 130-205 of human LASP1 (NP_006139.1).
This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer.
Purification Method:
Affinity purification
Gene ID:
3927
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using LASP1 Rabbit pAb (CAB3941) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
