UniProt Protein Function: | LARS2: a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. [provided by RefSeq, Jul 2008]Protein type: Translation; Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; Mitochondrial; Ligase; EC 6.1.1.4Chromosomal Location of Human Ortholog: 3p21.3Cellular Component: mitochondrion; mitochondrial matrix; cytosolMolecular Function: leucine-tRNA ligase activity; ATP bindingBiological Process: leucyl-tRNA aminoacylation; tRNA aminoacylation for protein translation; regulation of translational fidelity; gene expressionDisease: Perrault Syndrome 4 |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q15031 |
NCBI GenInfo Identifier: | 2501029 |
NCBI Gene ID: | 23395 |
NCBI Accession: | Q15031.2 |
UniProt Secondary Accession: | Q15031 |
UniProt Related Accession: | Q15031 |
Molecular Weight: | 903 |
NCBI Full Name: | Probable leucine--tRNA ligase, mitochondrial |
NCBI Synonym Full Names: | leucyl-tRNA synthetase 2, mitochondrial |
NCBI Official Symbol: | LARS2Â Â |
NCBI Official Synonym Symbols: | LEURS; PRLTS4Â Â |
NCBI Protein Information: | probable leucine--tRNA ligase, mitochondrial; leucine translase; leucine tRNA ligase 2, mitocondrial; leucine tRNA ligase 2, mitochondrial; probable leucyl-tRNA synthetase, mitochondrial |
UniProt Protein Name: | Probable leucine--tRNA ligase, mitochondrial |
UniProt Synonym Protein Names: | Leucyl-tRNA synthetase; LeuRS |
Protein Family: | Probable leucine--tRNA ligase |
UniProt Gene Name: | LARS2Â Â |
UniProt Entry Name: | SYLM_HUMAN |