The LARP1B Polyclonal Antibody (CAB13222) is a valuable tool for researchers studying the LARP1B protein, which plays a crucial role in RNA metabolism and translation regulation. This antibody, generated in rabbits, offers high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the LARP1B protein, researchers can accurately detect and analyze its expression in various cell types, making it an excellent choice for investigations in molecular biology and cancer research.
LARP1B is known for its involvement in multiple cellular processes, including mRNA stability and translation control, making it a promising target for studying diseases such as cancer and neurodevelopmental disorders. By gaining a deeper understanding of LARP1B's function, researchers can potentially uncover new therapeutic targets and strategies for treating these conditions. The LARP1B Polyclonal Antibody is a critical tool for advancing research in these areas and beyond.
Product Name:
LARP1B Rabbit Polyclonal Antibody
SKU:
CAB13222
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 170-320 of human LARP1B (NP_060548.2).
This gene encodes a protein containing domains found in the La related protein of Drosophila melanogaster. La motif-containing proteins are thought to be RNA-binding proteins, where the La motif and adjacent amino acids fold into an RNA recognition motif. The La motif is also found in proteins unrelated to the La protein. Alternative splicing has been observed at this locus and multiple variants, encoding distinct isoforms, are described. Additional splice variation has been identified but the full-length nature of these transcripts has not been determined.
Purification Method:
Affinity purification
Gene ID:
55132
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LARP1B Rabbit pAb (CAB13222) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.