The LARP1 Polyclonal Antibody (CAB4543) is a valuable tool for researchers studying LARP1, a protein involved in mRNA translation and stability. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding to the LARP1 protein, this antibody allows for the detection and analysis of LARP1 in various cell types, making it ideal for studies in molecular biology and cancer research.LARP1, also known as La-related protein 1, plays a crucial role in the regulation of mRNA metabolism and is implicated in various cellular processes such as cell proliferation and differentiation.
Dysregulation of LARP1 has been associated with cancer progression and other diseases, making it a promising target for therapeutic interventions. This antibody provides researchers with a valuable tool for exploring the function of LARP1 and its potential role in disease mechanisms.
Product Name:
LARP1 Rabbit Polyclonal Antibody
SKU:
CAB4543
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 106-205 of human LARP1 (Q6PKG0).
Enables eukaryotic initiation factor 4E binding activity; nucleic acid binding activity; and ribosomal small subunit binding activity. Involved in several processes, including TORC1 signaling; cellular response to rapamycin; and posttranscriptional regulation of gene expression. Located in cytoplasmic stress granule. Colocalizes with TORC1 complex and polysomal ribosome.
Purification Method:
Affinity purification
Gene ID:
23367
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using LARP1 Antibody (CAB4543) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
