The LAPTM5 Polyclonal Antibody (CAB17995) is a valuable tool for research involving LAPTM5, a lysosomal protein involved in protein trafficking and degradation. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the LAPTM5 protein, it enables precise detection and analysis in various cell types, making it an essential component for studies in molecular biology and lysosomal biology.LAPTM5, also known as lysosome-associated protein transmembrane 5, plays a crucial role in maintaining cellular homeostasis by facilitating the degradation of proteins within lysosomes.
Its involvement in protein trafficking pathways makes it a key player in cellular processes such as autophagy and antigen presentation. Understanding the function of LAPTM5 is essential for unraveling the mechanisms underlying lysosomal dysfunction and its implications in diseases like neurodegenerative disorders and lysosomal storage diseases. Researchers can utilize this antibody to further explore the role of LAPTM5 in cellular processes and disease pathology, paving the way for potential therapeutic interventions.
Product Name:
LAPTM5 Rabbit Polyclonal Antibody
SKU:
CAB17995
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 153-262 of human LAPTM5 (NP_006753.1).
cytoplasmic vesicle, cytosol, lysosome, perinuclear region of cytoplasm, plasma membrane, transport vesicle
Calculated MW:
30kDa
Observed MW:
25kDa
This gene encodes a transmembrane receptor that is associated with lysosomes. The encoded protein, also known as E3 protein, may play a role in hematopoiesis.
Purification Method:
Affinity purification
Gene ID:
7805
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using LAPTM5 antibody (CAB17995) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
