LANCL2 Antibody (PACO58476)
- SKU:
- PACO58476
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | LANCL2 Antibody (PACO58476) |
| Antibody SKU: | PACO58476 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human LanC-like protein 2 protein (2-106AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: A549 whole cell lysate, U87 whole cell lysate. All lanes: LANCL2 antibody at 3.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 51 kDa. Observed band size: 51 kDa. |
 | Immunofluorescence staining of HepG2 cells with PACO58476 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | IHC image of PACO58476 diluted at 1:300 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Necessary for abscisic acid, (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes. |
| Synonyms: | LanC-like protein 2 (Testis-specific adriamycin sensitivity protein), LANCL2, GPR69B TASP |
| UniProt Protein Function: | LANCL2: Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes. Belongs to the LanC-like protein family.Protein type: Unknown functionChromosomal Location of Human Ortholog: 7q31.1-q31.33Cellular Component: cortical actin cytoskeleton; cytoplasm; cytosol; nucleus; plasma membraneMolecular Function: ATP binding; catalytic activity; GTP binding; phosphatidylinositol 3-phosphate binding; phosphatidylinositol-5-phosphate binding; protein bindingBiological Process: metabolic process; negative regulation of transcription, DNA-dependent; positive regulation of abscisic acid mediated signaling |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9NS86 |
| NCBI GenInfo Identifier: | 8923911 |
| NCBI Gene ID: | 55915 |
| NCBI Accession: | NP_061167 |
| UniProt Secondary Accession: | Q9NS86,Q6NSL4, Q8TCQ3, Q9BSR1, B2R8D4 |
| UniProt Related Accession: | Q9NS86 |
| Molecular Weight: | Predicted: 50 kDaObserved: 48 kDa |
| NCBI Full Name: | lanC-like protein 2 |
| NCBI Synonym Full Names: | LanC like 2 |
| NCBI Official Symbol: | LANCL2Â Â |
| NCBI Official Synonym Symbols: | TASP; GPR69BÂ Â |
| NCBI Protein Information: | lanC-like protein 2 |
| UniProt Protein Name: | LanC-like protein 2 |
| UniProt Synonym Protein Names: | Testis-specific adriamycin sensitivity protein |
| Protein Family: | LanC-like protein |
| UniProt Gene Name: | LANCL2Â Â |
| UniProt Entry Name: | LANC2_HUMAN |