The Lamtor1 Polyclonal Antibody (CAB11619) is specifically designed for research involving Lamtor1, a protein involved in the regulation of cell growth and proliferation. This antibody, generated in rabbits, is highly reactive with human samples and is validated for use in Western blot applications. By targeting the Lamtor1 protein, researchers can detect and analyze its expression in various cell types, making it an essential tool for studies in cell biology and cancer research.Lamtor1, also known as MAPK and MTOR activator 1, is a key player in the mTORC1 signaling pathway, which controls cell growth and metabolism in response to nutrient availability.
Dysregulation of this pathway is implicated in various diseases, including cancer and metabolic disorders. By studying the function of Lamtor1, researchers can gain insights into the molecular mechanisms underlying these diseases and identify potential therapeutic targets for intervention.Overall, the Lamtor1 Polyclonal Antibody is a valuable tool for researchers investigating the role of Lamtor1 in cellular processes and disease pathology. Its high specificity and sensitivity make it an essential component of any research project aimed at unraveling the complex functions of this critical protein.
Product Name:
LAMTOR1 Rabbit Polyclonal Antibody
SKU:
CAB11619
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-161 of human LAMTOR1 (NP_060377.1).
Cell membrane, Cytoplasmic side, Late endosome membrane, Lipid-anchor, Lysosome membrane.
Calculated MW:
18kDa
Observed MW:
18kDa
Enables GTPase binding activity. Contributes to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Involved in several processes, including cholesterol homeostasis; positive regulation of TOR signaling; and regulation of cholesterol transport. Located in lysosome. Part of Ragulator complex.
Purification Method:
Affinity purification
Gene ID:
55004
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunofluorescence analysis of C6 cells using LAMTOR1 Rabbit pAb (CAB11619) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
