The LAMP3 Polyclonal Antibody (CAB2895) is a high-quality antibody designed for research involving LAMP3, a cell surface protein known to play a role in lysosome-related organelles. This polyclonal antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications, including Western blotting.LAMP3, also known as CD208, is a key player in the process of antigen presentation and immune responses. It is involved in the regulation of autophagy and plays a role in the immune response to pathogens. The LAMP3 Polyclonal Antibody specifically binds to the LAMP3 protein, allowing for the detection and analysis of LAMP3 expression in different cell types.
Research involving LAMP3 is crucial for understanding its role in immune responses, autophagy, and lysosome function. This antibody is an essential tool for studies in immunology, infectious diseases, and cancer research, providing valuable insights into the mechanisms underlying these biological processes. Harnessing the potential of LAMP3 may lead to the development of novel therapeutic strategies for a range of diseases.
Product Name:
LAMP3 Rabbit Polyclonal Antibody
SKU:
CAB2895
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 140-380 of human LAMP3 (NP_055213.2).
LAMP; CD208; DCLAMP; LAMP-3; TSC403; DC LAMP; DC-LAMP; LAMP3
Positive Sample:
Raji
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasmic vesicle membrane, Lysosome membrane, Single-pass type I membrane protein.
Calculated MW:
44kDa
Observed MW:
70kDa
Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).
Purification Method:
Affinity purification
Gene ID:
27074
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using LAMP3 Rabbit pAb (CAB2895) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
