The LAMP2A Rabbit Monoclonal Antibody is a high-quality antibody designed for research involving LAMP2A, a lysosomal membrane protein involved in autophagy and lysosomal biogenesis. This antibody is raised in rabbits and is highly reactive with human samples, making it ideal for use in Western blot and immunohistochemistry applications. LAMP2A plays a crucial role in maintaining cellular homeostasis by facilitating the degradation of damaged organelles and proteins through the autophagy-lysosomal pathway.
Dysregulation of autophagy has been implicated in various diseases, including neurodegenerative disorders, cancer, and metabolic conditions. By using the LAMP2A Rabbit Monoclonal Antibody, researchers can accurately detect and study the expression and localization of LAMP2A in different cell types and tissues. This antibody's specificity and sensitivity make it a valuable tool for investigating the role of autophagy in disease pathogenesis and identifying potential therapeutic targets for intervention.
Product Name:
LAMP2 Rabbit Monoclonal Antibody
SKU:
CAB0593
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 311-410 of human LAMP2 (P13473).
Cell membrane, Endosome membrane, Lysosome membrane, Single-pass type I membrane protein.
Calculated MW:
45kDa
Observed MW:
100-120kDa
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins.
Purification Method:
Affinity purification
Gene ID:
3920
Clone Number:
ARC0274
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from A-549 cells, using LAMP2 Rabbit mAb (CAB0593) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
