The LAMP2 Polyclonal Antibody (CAB1961) is a valuable tool for researchers studying lysosomal-associated membrane protein 2 (LAMP2) in various biological processes. LAMP2 is a glycoprotein found in lysosomal membranes and plays a crucial role in lysosomal biogenesis and autophagy. This polyclonal antibody, produced in rabbits, displays high reactivity with human samples and is verified for use in Western blot applications. By binding to the LAMP2 protein, this antibody allows for accurate detection and analysis in a wide range of cell types. With its specificity and sensitivity, it is particularly suited for studies in cell biology, molecular biology, and disease research.
Intracellular trafficking, autophagy, and lysosomal functions are key areas of study where the LAMP2 antibody can provide valuable insights. By understanding the roles of LAMP2 in these processes, researchers can shed light on various diseases, including neurodegenerative disorders, metabolic disorders, and lysosomal storage diseases. The LAMP2 Polyclonal Antibody is an essential tool for unraveling the complex mechanisms involving LAMP2 and its impact on cellular functions.
Product Name:
LAMP2 Rabbit Polyclonal Antibody
SKU:
CAB1961
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 29-375 of human LAMP2 (NP_002285.1).
Cell membrane, Endosome membrane, Lysosome membrane, Single-pass type I membrane protein.
Calculated MW:
45kDa
Observed MW:
100-130kDa
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins.
Purification Method:
Affinity purification
Gene ID:
3920
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using LAMP2 antibody (CAB1961) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
