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LAMP1 Polyclonal Antibody (CAB21480)

SKU:
CAB21480
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Isotype:
IgG
Applications:
WB
$155 - $431
Frequently bought together:

Description

LAMP1 Polyclonal Antibody (CAB21480)

The LAMP1 Polyclonal Antibody (CAB21480) is a valuable tool for research involving LAMP1, a lysosomal membrane protein involved in cellular processes such as lysosomal biogenesis, autophagy, and endocytosis. This rabbit-raised antibody is highly specific to human samples and is validated for use in Western blot applications. By binding to the LAMP1 protein, this antibody enables the detection and analysis of LAMP1 expression in various cell types, making it a versatile option for studies in cell biology and cancer research.

LAMP1, also known as lysosomal-associated membrane protein 1, plays a crucial role in the maintenance of lysosomal function and the degradation of cellular components. Dysregulation of LAMP1 has been implicated in diseases such as cancer, neurodegenerative disorders, and lysosomal storage diseases. By studying the expression and function of LAMP1, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets.

Product Name:LAMP1 Polyclonal Antibody
Product Code:CAB21480
Reactivity:Human
Applications:Western blotting
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Positive Samples:U-937
Cellular Location:Cell membrane, Endosome membrane, Late endosome, Lysosome membrane, Single-pass type I membrane protein

The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis.

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 150-250 of human LAMP1 (NP_005552.3).
Sequence:DKKYR CVSGT QVHMN NVTVT LHDAT IQAYL SNSSF SRGET RCEQD RPSPT TAPPA PPSPS PSPVP KSPSV DKYNV SGTNG TCLLA SMGLQ LNLTY ERKDN T
Synonyms:LAMPA, CD107a, LGP120
Calculated MW:45kDa
Observed MW:90-120kDa

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