The LAIR2 Polyclonal Antibody (CAB14376) is a valuable tool for researchers studying the LAIR2 protein, a member of the leukocyte-associated immunoglobulin-like receptor (LAIR) family. LAIR2 is known to modulate immune responses by interacting with collagen, thus regulating various immune processes such as inflammation and immune cell activation. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications, allowing for accurate detection and analysis of LAIR2 protein levels in different cell types.
Its high reactivity and specificity make it an ideal tool for immunological studies focusing on immune regulation and its involvement in diseases such as autoimmune disorders and cancer.Understanding the role of LAIR2 in immune modulation is crucial for developing targeted therapies that could potentially manipulate immune responses for therapeutic purposes. Researchers looking to investigate the intricate mechanisms of immune regulation and its implications in diseases will find this LAIR2 Polyclonal Antibody essential for their studies.
Product Name:
LAIR2 Rabbit Polyclonal Antibody
SKU:
CAB14376
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-120 of human LAIR2 (NP_002279.2).
The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to leukocyte-associated immunoglobulin-like receptor 1, a membrane-bound receptor that modulates innate immune response. The protein encoded by this locus is a soluble receptor that may play roles in both inhibition of collagen-induced platelet aggregation and vessel formation during placental implantation. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily. Alternatively spliced transcript variants have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
3904
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LAIR2 Rabbit pAb (CAB14376) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
