LAIR1 Rabbit Polyclonal Antibody (CAB10120)
- SKU:
- CAB10120
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | LAIR1 Rabbit Polyclonal Antibody |
SKU: | CAB10120 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-163 of human LAIR1 (NP_002278.2). |
Sequence: | QEED LPRP SISA EPGT VIPL GSHV TFVC RGPV GVQT FRLE RDSR STYN DTED VSQA SPSE SEAR FRID SVRE GNAG LYRC IYYK PPKW SEQS DYLE LLVK ESSG GPDS PDTE PGSS AGPT QRPS DNSH NEHA PASQ GLKA EH |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CD305; LAIR-1; LAIR1 |
Positive Sample: | THP-1,HL-60,U-937 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 31kDa |
Observed MW: | 40-60kDa |
The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 3903 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |