Description
Product Name: | Ku80 Polyclonal Antibody |
SKU: | CAB24867 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 543-732 of mouse Ku80 (NP_033559.2). |
Sequence: | IKKK NQVT AQDV FQDN HEEG PAAK KYKT EKEE DHIS ISSL AEGN ITKV GSVN PVEN FRFL VRQK IASF EEAS LQLI SHIE QFLD TNET LYFM KSMD CIKA FREE AIQF SEEQ RFNS FLEA LREK VEIK QLNH FWEI VVQD GVTL ITKD EGPG SSIT AEEA TKFL APKD KAKE DTTG PEEA GDVD DLLD MI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | Ku80; Ku86; CTC85; CTCBF |
Positive Sample: | NIH/3T3,Neuro-2a,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, Nucleus, nucleolus |
Calculated MW: | 83kDa |
Observed MW: | 83kDa |
Predicted to enable several functions, including nucleic acid binding activity; protein C-terminus binding activity; and ubiquitin protein ligase binding activity. Predicted to contribute to 5'-deoxyribose-5-phosphate lyase activity and double-stranded telomeric DNA binding activity. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; hematopoietic stem cell differentiation; and positive regulation of neurogenesis. Located in cytoplasm and nucleus. Is expressed in thymus primordium. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease and multiple myeloma. Orthologous to human XRCC5 (X-ray repair cross complementing 5).
Purification Method: | Affinity purification |
Gene ID: | 22596 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |