Ku70 Rabbit Monoclonal Antibody (CAB11223)
- SKU:
- CAB11223
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | Ku70 Rabbit Monoclonal Antibody |
SKU: | CAB11223 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 500-609 of human Ku70 (P12956). |
Sequence: | PEQA VDLT LPKV EAMN KRLG SLVD EFKE LVYP PDYN PEGK VTKR KHDN EGSG SKRP KVEY SEEE LKTH ISKG TLGK FTVP MLKE ACRA YGLK SGLK KQEL LEAL TKHF QD |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | ML8; KU70; TLAA; CTC75; CTCBF; G22P1; Ku70 |
Positive Sample: | HeLa,293T,Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus. |
Calculated MW: | 70kDa |
Observed MW: | 70kDa |
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Purification Method: | Affinity purification |
Gene ID: | 2547 |
Clone Number: | ARC0551 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |