The KTN1 Polyclonal Antibody (CAB12456) is a powerful tool for researchers studying the KTN1 protein, a key player in cell division and cytoskeletal organization. This antibody, derived from rabbit serum, shows high specificity and sensitivity towards KTN1 in human samples, making it an ideal choice for Western blot applications. By targeting the KTN1 protein, this antibody enables accurate detection and analysis in various cell types, allowing for in-depth studies in areas such as cell biology and cancer research.KTN1, also known as kinectin, is essential for proper cell division and organization of the cytoskeleton, making it a crucial protein for maintaining cellular function and structure.
Research into KTN1 can provide valuable insights into processes such as mitosis, cell migration, and intracellular transport. Understanding the function and regulation of KTN1 is key to unraveling its role in diseases such as cancer, where abnormal cell division and cytoskeletal abnormalities are common features.By using the KTN1 Polyclonal Antibody, researchers can delve deeper into the complex mechanisms involving KTN1 and its impact on cellular processes. This antibody serves as a reliable tool for investigating KTN1-related pathways and functions, paving the way for advancements in our understanding of cell biology and disease pathology.
Product Name:
KTN1 Rabbit Polyclonal Antibody
SKU:
CAB12456
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human KTN1 (NP_001072989.1).
Endoplasmic reticulum membrane, Single-pass type II membrane protein.
Calculated MW:
156kDa
Observed MW:
178kDa
This gene encodes an integral membrane protein that is a member of the kinectin protein family. The encoded protein is primarily localized to the endoplasmic reticulum membrane. This protein binds kinesin and may be involved in intracellular organelle motility. This protein also binds translation elongation factor-delta and may be involved in the assembly of the elongation factor-1 complex. Alternate splicing results in multiple transcript variants of this gene.
Purification Method:
Affinity purification
Gene ID:
3895
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using KTN1 antibody (CAB12456) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.