The KRTAP8-1 Antibody (PAC03774) is a high-quality polyclonal antibody designed for research involving KRTAP8-1, a protein found in human hair follicles. This antibody is raised in rabbits and is highly reactive with human samples, making it ideal for studies focused on hair biology and dermatology. It has been validated for use in various applications, including Western blotting, immunohistochemistry, and ELISA.KRTAP8-1 is a keratin-associated protein known for its role in hair structure and development. It is highly expressed in the cortex of human hair fibers and contributes to the strength and elasticity of hair.
Research on KRTAP8-1 can provide valuable insights into hair growth, hair disorders, and cosmetic applications.The KRTAP8-1 Antibody (PAC03774) enables researchers to detect and analyze KRTAP8-1 protein levels in different cell types and tissues, facilitating studies on hair biology, hair disorders, and potential therapeutic interventions. Its specificity and sensitivity make it a valuable tool for investigating the functions and roles of KRTAP8-1 in various research settings.
Antibody Name:
KRTAP8-1 Antibody (PACO37774)
Antibody SKU:
PACO37774
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Keratin-associated protein 8-1 protein (1-63AA)
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO37774 at dilution of 1:100.
Background:
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Synonyms:
Keratin-associated protein 8-1 (High glycine-tyrosine keratin-associated protein 8.1), KRTAP8-1, KAP8.1 KRTAP8.1
UniProt Protein Function:
KRTAP8-1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. Belongs to the KRTAP type 8 family.Chromosomal Location of Human Ortholog: 21q22.1Cellular Component: intermediate filament
