Similarly, the KRTAP3-2 Antibody (PAC041014) offered by AssayGenie is a valuable tool for researchers studying keratin-associated proteins. Keratin proteins are essential components of hair and skin, providing structure and protection. KRTAP3-2 is a specific type of keratin-associated protein that plays a role in hair development and maintenance.This polyclonal antibody, produced in rabbits, has been validated for use in various applications, including immunofluorescence, immunohistochemistry, and Western blotting. It specifically binds to KRTAP3-2, allowing for the detection and analysis of this protein in different tissue samples.
Research involving KRTAP3-2 can provide insights into hair biology, dermatology, and even forensic science. By studying the expression and function of KRTAP3-2, scientists can better understand hair growth and disorders, as well as potentially develop new treatments for various skin conditions.Overall, the KRTAP3-2 Antibody (PAC041014) is a reliable tool for researchers looking to explore the role of keratin-associated proteins in hair biology and skin health. Its specificity and sensitivity make it a valuable asset for studies in these fields.
Antibody Name:
KRTAP3-2 Antibody (PACO41014)
Antibody SKU:
PACO41014
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Keratin-associated protein 3-2 protein (2-98AA)
Immunohistochemistry of paraffin-embedded human skin tissue using PACO41014 at dilution of 1:100.
Background:
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Synonyms:
Keratin-associated protein 3-2 (High sulfur keratin-associated protein 3.2) (Keratin-associated protein 3.2), KRTAP3-2, KAP3.2 KRTAP3.2
UniProt Protein Function:
KRTAP3-2: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. Belongs to the KRTAP type 3 family.Chromosomal Location of Human Ortholog: 17q21.2Molecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008]
