The KRTAP23-1 Antibody (PAC027877) is a polyclonal antibody developed for research involving KRTAP23-1, a protein that belongs to the keratin-associated protein family. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blotting.KRTAP23-1 is a crucial component involved in hair structure and function, making it a target of interest in studies related to hair biology and dermatology. By using the KRTAP23-1 Antibody, researchers can detect and analyze the expression of KRTAP23-1 in different cell types, providing valuable insights into its role in hair development and maintenance.
Understanding the function of KRTAP23-1 can have implications for research into hair disorders, genetic conditions affecting hair growth, as well as potential applications in the cosmetic and pharmaceutical industries. With its high specificity and reliability, the KRTAP23-1 Antibody is a valuable tool for researchers looking to delve deeper into the role of KRTAP23-1 in hair biology.
Antibody Name:
KRTAP23-1 Antibody (PACO27877)
Antibody SKU:
PACO27877
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Keratin-associated protein 23-1 protein (1-65AA)
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO27877 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO27877 at dilution of 1:100.
Background:
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Synonyms:
Keratin-associated protein 23-1, KRTAP23-1, KAP23.1
UniProt Protein Function:
KRTAP23-1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.Chromosomal Location of Human Ortholog: 21q22.1Cellular Component: intermediate filament
