The KRTAP13-3 Polyclonal Antibody (PAC035974) is a powerful tool for researchers studying the keratin-associated protein 13-3 (KRTAP13-3), a protein present in hair and associated with hair formation and structure. This antibody, generated in rabbits, exhibits high specificity and sensitivity when used with human samples, making it an invaluable resource for Western blot applications. By targeting the KRTAP13-3 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in fields such as dermatology and hair biology.
KRTAP13-3 is a key player in the development and maintenance of hair fibers, making it a focal point for research in hair growth and disorders such as alopecia. Understanding the function and regulation of KRTAP13-3 provides insight into hair biology and has implications for the development of treatments for hair-related conditions. With its ability to target KRTAP13-3, this antibody facilitates exploration into the role of this protein in hair development and pathology, offering valuable information for researchers in the field.
Antibody Name:
KRTAP13-3 Antibody (PACO35974)
Antibody SKU:
PACO35974
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Keratin-associated protein 13-3 protein (1-172AA)
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Synonyms:
Keratin-associated protein 13-3, KRTAP13-3, KAP13.3
UniProt Protein Function:
KRTAP13-3: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. Belongs to the PMG family.Chromosomal Location of Human Ortholog: 21q22.1Molecular Function: protein binding