The KRTAP11-1 Antibody (PAC037654) is a polyclonal antibody designed for research involving KRTAP11-1, a protein associated with hair fiber formation and structure. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it an ideal tool for studying the role of KRTAP11-1 in hair biology.KRTAP11-1 is a keratin-associated protein known to play a crucial role in the structural integrity and growth of hair fibers. Its expression is primarily found in the hair follicles, where it contributes to the overall strength and resilience of the hair shaft. Research into KRTAP11-1 is essential for understanding the mechanisms underlying hair growth and development, as well as potential implications for hair disorders and cosmetic applications.
By using the KRTAP11-1 Antibody, researchers can detect and analyze the expression of KRTAP11-1 in various cell types and tissues, providing valuable insights into its function in hair biology. This antibody is validated for use in Western blot applications, making it a versatile tool for studies focused on hair fiber formation, structural abnormalities, and potential therapeutic targets in hair-related conditions.
Antibody Name:
KRTAP11-1 Antibody (PACO37654)
Antibody SKU:
PACO37654
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Keratin-associated protein 11-1 protein (1-186AA)
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Synonyms:
Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1), KRTAP11-1, KAP11.1 KRTAP11.1
UniProt Protein Function:
KRTAP11-1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. Belongs to the PMG family.Chromosomal Location of Human Ortholog: 21q22.1Cellular Component: keratin filamentMolecular Function: structural molecule activity
