KRT81 Rabbit Polyclonal Antibody (CAB3940)
- SKU:
- CAB3940
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | KRT81 Rabbit Polyclonal Antibody |
SKU: | CAB3940 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human KRT81 (NP_002272.2). |
Sequence: | VAQS EQQG EAAL SDAR CKLA ELEG ALQK AKQD MACL IREY QEVM NSKL GLDI EIAT YRRL LEGE EQRL CEGI GAVN VCVS SSRG GVVC GDLC VSGS RPVT G |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | HB1; K81; Hb-1; KRTHB1; MLN137; ghHkb1; hHAKB2-1; KRT81 |
Positive Sample: | 293T,NCI-H460,MCF7,Mouse ovary,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, extracellular space |
Calculated MW: | 55kDa |
Observed MW: | 55kDa |
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
Purification Method: | Affinity purification |
Gene ID: | 3887 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |