The KRT77 Polyclonal Antibody (PAC037218) is a powerful tool for researchers studying Keratin 77, a type II cytokeratin protein found in hair follicles and nail beds. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples and has been validated for use in various applications, including Western blotting.Keratin 77 plays a crucial role in the structural integrity of hair and nails, making it a key focus in dermatological and cosmetic research. The KRT77 Polyclonal Antibody binds specifically to KRT77, allowing for accurate detection and analysis in a variety of cell types.
This makes it an essential tool for investigating hair and nail disorders, as well as for exploring the potential use of KRT77 as a biomarker in cancer research.By studying the function and expression of KRT77, researchers can gain insights into the development and maintenance of hair and nails, as well as potentially uncovering new therapeutic targets for conditions related to keratin disorders. The KRT77 Polyclonal Antibody is a valuable resource for scientists looking to advance their understanding of the role of KRT77 in health and disease.
Antibody Name:
KRT77 Antibody (PACO37218)
Antibody SKU:
PACO37218
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Keratin, type II cytoskeletal 1b protein (1-578AA)
Immunohistochemistry of paraffin-embedded human skin tissue using PACO37218 at dilution of 1:100.
Synonyms:
Keratin, type II cytoskeletal 1b (Cytokeratin-1B) (CK-1B) (Keratin-77) (K77) (Type-II keratin Kb39), KRT77, KRT1B
UniProt Protein Function:
K77: Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in the skin and eccrine sweat glands. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]Protein type: CytoskeletalChromosomal Location of Human Ortholog: 12q13.13Cellular Component: cytoskeleton
UniProt Protein Details:
NCBI Summary:
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in the skin and eccrine sweat glands. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]
