| UniProt Protein Function: | KRT72: Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable). Belongs to the intermediate filament family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: CytoskeletalChromosomal Location of Human Ortholog: 12q13.13Cellular Component: keratin filamentMolecular Function: structural molecule activity |
| UniProt Protein Details: | |
| NCBI Summary: | Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2009] |
| UniProt Code: | Q14CN4 |
| NCBI GenInfo Identifier: | 166218813 |
| NCBI Gene ID: | 140807 |
| NCBI Accession: | Q14CN4.2 |
| UniProt Secondary Accession: | Q14CN4,Q8NA87, Q8WWY9, Q8WWZ0, B4DEI8, H9KV51 |
| UniProt Related Accession: | Q14CN4 |
| Molecular Weight: | 55,877 Da |
| NCBI Full Name: | Keratin, type II cytoskeletal 72 |
| NCBI Synonym Full Names: | keratin 72 |
| NCBI Official Symbol: | KRT72Â Â |
| NCBI Official Synonym Symbols: | KRT6; K6irs; K6IRS2; KRT6IRS2Â Â |
| NCBI Protein Information: | keratin, type II cytoskeletal 72; K72; CK-72; keratin-72; cytokeratin-72; type-II keratin Kb35; keratin protein K6irs; keratin 6, inner root sheath, 2; type II inner root sheath-specific keratin-K6irs2 |
| UniProt Protein Name: | Keratin, type II cytoskeletal 72 |
| UniProt Synonym Protein Names: | Cytokeratin-72; CK-72; Keratin-72; K72; Type II inner root sheath-specific keratin-K6irs2; Type-II keratin Kb35 |
| Protein Family: | Keratin |
| UniProt Gene Name: | KRT72Â Â |
| UniProt Entry Name: | K2C72_HUMAN |
