The KRT7 Polyclonal Antibody (CAB2574) is a valuable tool for researchers studying the role of KRT7 in cancer and cell biology. This antibody, generated in rabbits, is highly specific and reacts with human samples in a variety of applications, including Western blot and immunohistochemistry.KRT7, also known as cytokeratin 7, is a type II cytokeratin protein that is expressed in epithelial cells, particularly in glandular and transitional epithelium. Aberrant expression of KRT7 has been observed in various types of cancer, making it a potential biomarker for diagnostic and prognostic purposes.
By using the KRT7 Polyclonal Antibody, researchers can detect and analyze KRT7 expression in different cell types and tissues, providing valuable insights into its function and potential role in disease progression. This antibody is a valuable tool for studies in cancer biology, cell differentiation, and tissue regeneration.
Product Name:
Cytokeratin 7 (KRT7) Rabbit Polyclonal Antibody
SKU:
CAB2574
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 230-469 of human Cytokeratin 7 (Cytokeratin 7 (KRT7)) (NP_005547.3).
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.
Purification Method:
Affinity purification
Gene ID:
3855
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of HeLa cells, using Cytokeratin 7 (Cytokeratin 7 (KRT7)) antibody (CAB2574).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
