KRT6B Rabbit Polyclonal Antibody (CAB7696)
- SKU:
- CAB7696
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | KRT6B Rabbit Polyclonal Antibody |
SKU: | CAB7696 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human KRT6B (NP_005546.2). |
Sequence: | MAST STTI RSHS SSRR GFSA NSAR LPGV SRSG FSSI SVSR SRGS GGLG GACG GAGF GSRS LYGL GGSK RISI GGGS CAIS GGYG SRAG GSYG FGGA GSGF GFGG GAGI GFGL GGGA GLAG GFGG PGFP VCPP GGIQ EVTV NQSL LTPL NLQI DPAI QRVR AEER EQIK TLNN KFAS FIDK VRFL EQQN KVLD TKWT LLQE QGTK TVRQ NLEP LFEQ YINN LRRQ LDNI VGER GRLD SELR NMQD LVED LKNK YEDE INKR TAAE NEFV TLKK DVDA AYMN |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | K6B; PC2; PC4; CK6B; CK-6B; KRTL1; KRT6B |
Positive Sample: | Mouse eye |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, extracellular exosome |
Calculated MW: | 60kDa |
Observed MW: | 60kDa |
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Purification Method: | Affinity purification |
Gene ID: | 3854 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |