The KRT40 Polyclonal Antibody (PACO36386) is a powerful tool for researchers studying keratin 40, a protein involved in the formation and maintenance of hair and nails. This antibody, produced in rabbits, displays high reactivity with human samples and is validated for use in Western blot applications. By targeting the KRT40 protein, this antibody allows for the detection and analysis of keratin 40 in a variety of cell types, making it an essential tool for studies in dermatology and hair biology research.Keratin 40 plays a vital role in the structural integrity and function of hair and nails, making it a key focus in understanding conditions such as alopecia and nail disorders.
By studying the expression and regulation of KRT40, researchers can gain valuable insights into the development and treatment of these conditions. The KRT40 Polyclonal Antibody opens up new avenues for exploring the role of keratin 40 in health and disease, offering potential therapeutic targets for various dermatological conditions.
Antibody Name:
KRT40 Antibody (PACO36386)
Antibody SKU:
PACO36386
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Keratin, type I cytoskeletal 40 protein (1-200AA)
Immunohistochemistry of paraffin-embedded human skin tissue using PACO36386 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO36386 at dilution of 1:100.
Background:
May play a role in late hair differentiation.
Synonyms:
Keratin, type I cytoskeletal 40 (Cytokeratin-40) (CK-40) (Keratin-40) (K40) (Type I hair keratin Ka36), KRT40, KA36
UniProt Protein Function:
May play a role in late hair differentiation.
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]
