The KRT40 Antibody (PACO14062) is a high-quality polyclonal antibody designed for research involving KRT40, a keratin protein associated with hair and skin development. This antibody, produced in rabbits, is highly specific to human samples and is suitable for use in various experimental applications, including Western blotting and immunohistochemistry.KRT40 is a key component of the hair shaft and plays a crucial role in maintaining hair structure and integrity. Research shows that mutations in the KRT40 gene can lead to hair disorders and abnormalities, making it a valuable target for studies related to hair biology and dermatology. The KRT40 Antibody allows for sensitive and precise detection of KRT40 protein levels in different cell types and tissues, making it an essential tool for investigating the function and regulation of this protein in health and disease.
By using the KRT40 Antibody in your research, you can gain valuable insights into the role of KRT40 in hair and skin biology, as well as its potential implications in conditions such as alopecia, hair loss, and skin disorders. This antibody is a reliable and effective tool for researchers in the fields of dermatology, hair biology, and molecular biology who are interested in unraveling the mysteries of KRT40 and its impact on human health.
Antibody Name:
KRT40 Antibody (PACO14062)
Antibody SKU:
PACO14062
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Fusion protein of human KRT40
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO14062(KRT40 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO14062(KRT40 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene encodes a member of the type I (acid, c) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21.
Synonyms:
keratin 40
UniProt Protein Function:
May play a role in late hair differentiation.
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]
