KRT38 Antibody (PACO27857)
- SKU:
- PACO27857
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
KRT38 Antibody (PACO27857)
The KRT38 Polyclonal Antibody (PAC027857) is a valuable tool for researchers studying the keratin 38 protein. Keratin 38 is a type I keratin protein that is involved in maintaining the structural integrity of epithelial cells, particularly in the hair and nails. This antibody, raised in rabbits, has been shown to be highly specific to human samples and is suitable for use in Western blot applications.By specifically binding to the KRT38 protein, this antibody enables researchers to detect and analyze levels of KRT38 in various cell types, providing insights into its role in epithelial cell function and development.
The KRT38 antibody is an essential tool for studies in dermatology, cell biology, and regenerative medicine, allowing for a better understanding of the mechanisms underlying epithelial cell differentiation and maintenance.Given the importance of keratins in maintaining tissue integrity and function, research into KRT38 is relevant to a wide range of skin disorders, hair disorders, and other conditions affecting epithelial tissues. The KRT38 Polyclonal Antibody is a valuable resource for researchers looking to advance our understanding of these processes and develop new therapeutic strategies for related diseases.
| Antibody Name: | KRT38 Antibody (PACO27857) |
| Antibody SKU: | PACO27857 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Keratin, type I cuticular Ha8 protein (2-456AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: KRT38 antibody at 2µg/ml Lane 1: MCF-7 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: HepG2 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 51 kDa Observed band size: 51 kDa . |
| Synonyms: | Keratin, type I cuticular Ha8 (Hair keratin, type I Ha8) (Keratin-38) (K38), KRT38, HHA8 HKA8 KRTHA8 |
| UniProt Protein Function: | KRT38: Belongs to the intermediate filament family |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 17q21.2 Cellular Component: intermediate filament Molecular Function:protein binding; structural molecule activity |
| NCBI Summary: | The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O76015 |
| NCBI GenInfo Identifier: | 15431318 |
| NCBI Gene ID: | 8687 |
| NCBI Accession: | NP_006762.3 |
| UniProt Secondary Accession: | O76015,Q6A164, A2RRM5, |
| UniProt Related Accession: | O76015 |
| Molecular Weight: | 50,480 Da |
| NCBI Full Name: | keratin, type I cuticular Ha8 |
| NCBI Synonym Full Names: | keratin 38, type I |
| NCBI Official Symbol: | KRT38Â Â |
| NCBI Official Synonym Symbols: | HA8; hHa8; KRTHA8Â Â |
| NCBI Protein Information: | keratin, type I cuticular Ha8 |
| UniProt Protein Name: | Keratin, type I cuticular Ha8 |
| UniProt Synonym Protein Names: | Hair keratin, type I Ha8; Keratin-38; K38 |
| Protein Family: | Keratin |
| UniProt Gene Name: | KRT38Â Â |
| UniProt Entry Name: | KRT38_HUMAN |
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