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KRT33B Antibody (PACO35638)

SKU:
PACO35638
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
  • KRT33B Antibody PACO35638
  • KRT33B Antibody PACO35638
  • KRT33B Antibody PACO35638
€339

Description

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KRT33B Antibody (PACO35638)

The KRT33B Antibody (PACO35638) is a highly specific polyclonal antibody designed for research involving KRT33B, a keratin protein expressed in hair follicle cells. This antibody, raised in rabbits, is reactive with human samples and is validated for use in various applications, including immunohistochemistry and immunofluorescence.KRT33B is a member of the keratin family, which plays a crucial role in maintaining the structural integrity of hair and nails. Research on KRT33B can provide insights into hair growth and disorders affecting the hair follicles.

The KRT33B Antibody enables detection and visualization of KRT33B protein in tissue samples, making it a valuable tool for studies in dermatology, hair biology, and cosmetology.Furthermore, understanding the expression and regulation of KRT33B can lead to advancements in the treatment of hair-related conditions, such as alopecia and hair loss. The KRT33B Antibody is essential for researchers looking to investigate the role of KRT33B in hair biology and develop innovative therapies for hair disorders.

Antibody Name:KRT33B Antibody (PACO35638)
Antibody SKU:PACO35638
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200
Species Reactivity:Human
Immunogen:Recombinant Human Keratin, type I cuticular Ha3-II protein (1-404AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:Antigen Affinity Purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageWestern blot. All lanes: KRT33B antibody at 1µg/ml + MCF-7 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 47 kDa. Observed band size: 47 kDa.
Product ImageImmunohistochemistry of paraffin-embedded human prostate cancer using PACO35638 at dilution of 1:100.
Product ImageImmunohistochemistry of paraffin-embedded human cervical cancer using PACO35638 at dilution of 1:100.
Background:There are two types of hair/microfibrillar keratin, I (acid, c) and II (neutral to basic).
Synonyms:Keratin, type I cuticular Ha3-II (Hair keratin, type I Ha3-II) (Keratin-33B) (K33B), KRT33B, HHA3-II HKA3B KRTHA3B
UniProt Protein Function:KRT33B: a member of the keratin gene family. This gene is one of multiple type I hair keratin genes that are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. As a type I hair keratin, the encoded protein is an acidic protein which heterodimerizes with type II keratins to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, keratin 33A and keratin 33B. [provided by RefSeq, May 2012]Protein type: Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 17q21.2Cellular Component: extracellular spaceMolecular Function: protein bindingBiological Process: aging; hair cycle
UniProt Protein Details:
NCBI Summary:This gene encodes a member of the keratin gene family. This gene is one of multiple type I hair keratin genes that are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. As a type I hair keratin, the encoded protein is an acidic protein which heterodimerizes with type II keratins to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, keratin 33A and keratin 33B. [provided by RefSeq, May 2012]
UniProt Code:Q14525
NCBI GenInfo Identifier:6686299
NCBI Gene ID:3884
NCBI Accession:Q14525.3
UniProt Secondary Accession:Q14525,O76010
UniProt Related Accession:Q14525
Molecular Weight:46,214 Da
NCBI Full Name:Keratin, type I cuticular Ha3-II
NCBI Synonym Full Names:keratin 33B
NCBI Official Symbol:KRT33B  
NCBI Official Synonym Symbols:K33B; HA3II; Ha-3II; KRTHA3A; KRTHA3B; hHa3-II  
NCBI Protein Information:keratin, type I cuticular Ha3-II
UniProt Protein Name:Keratin, type I cuticular Ha3-II
UniProt Synonym Protein Names:Hair keratin, type I Ha3-II; Keratin-33B; K33B
Protein Family:Keratin
UniProt Gene Name:KRT33B  
UniProt Entry Name:KT33B_HUMAN
Antibodies
KRT33B Antibody (PACO10168)
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
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