KRT31 Antibody (PACO14066)
- SKU:
- PACO14066
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
KRT31 Antibody (PACO14066)
The Krt31 Antibody (PAC014066) offered by Assay Genie is a polyclonal antibody designed for research involving Keratin 31 (Krt31), a protein that is a member of the intermediate filament family. This antibody is raised in rabbits and is highly reactive with human samples, making it ideal for use in various research applications.Keratin 31 is known to be expressed in the hair follicles, specifically the cortex of the hair shaft, and plays a role in maintaining the structural integrity of hair. Research has shown that abnormalities in Krt31 expression can lead to hair disorders and conditions such as alopecia.
The Krt31 Antibody binds specifically to the Krt31 protein, allowing for its detection and analysis in various cell types and tissues. This antibody can be utilized in techniques such as Western blotting, immunofluorescence, and immunohistochemistry to study the expression and function of Krt31 in different biological contexts.Overall, the Krt31 Antibody is a valuable tool for researchers studying hair biology, skin disorders, and keratinocyte function. Its high specificity and reactivity make it a reliable choice for investigating the role of Krt31 in various physiological and pathological conditions.
| Antibody Name: | KRT31 Antibody (PACO14066) |
| Antibody SKU: | PACO14066 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human KRT31 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO14066(KRT31 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human normal liver tissue, Primary antibody: PACO14066(KRT31 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO14066(KRT31 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acid, c protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. |
| Synonyms: | Keratin-31 |
| UniProt Protein Function: | KRT31: is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cytoskeletal Chromosomal Location of Human Ortholog: 17q21.2 Cellular Component: extracellular space; intermediate filament Molecular Function:structural constituent of cytoskeleton Biological Process: epidermis development |
| NCBI Summary: | The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q15323 |
| NCBI GenInfo Identifier: | 209572740 |
| NCBI Gene ID: | 3881 |
| NCBI Accession: | Q15323.3 |
| UniProt Secondary Accession: | Q15323,O76009, Q14525, O76011, |
| UniProt Related Accession: | Q15323 |
| Molecular Weight: | 416 |
| NCBI Full Name: | Keratin, type I cuticular Ha1 |
| NCBI Synonym Full Names: | keratin 31 |
| NCBI Official Symbol: | KRT31Â Â |
| NCBI Official Synonym Symbols: | HA1; Ha-1; hHa1; KRTHA1Â Â |
| NCBI Protein Information: | keratin, type I cuticular Ha1; K31; keratin-31; hard keratin, type I, 1; keratin, hair, acidic,1; hair keratin, type I Ha1 |
| UniProt Protein Name: | Keratin, type I cuticular Ha1 |
| UniProt Synonym Protein Names: | Hair keratin, type I Ha1; Keratin-31; K31 |
| UniProt Gene Name: | KRT31Â Â |
| UniProt Entry Name: | K1H1_HUMAN |
Related Products
KRT31 Antibody (PACO14065)
