KRT31 Antibody (PACO14065)
- SKU:
- PACO14065
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
KRT31 Antibody (PACO14065)
The KRT31 Polyclonal Antibody (PAC014065) is a valuable tool for research involving KRT31, a protein belonging to the keratin family that is important for the structural integrity of hair and nails. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in various applications including Western blot and immunohistochemistry.KRT31 is involved in the formation and maintenance of hair fibers, making it a key player in research related to hair growth disorders, alopecia, and other dermatological conditions.
Its expression is also found in certain cancer types, highlighting its potential as a biomarker for diagnostic and therapeutic purposes.With its high reactivity and specificity, the KRT31 Polyclonal Antibody is a reliable tool for studying the functions and regulation of KRT31 in different biological contexts. Whether investigating normal hair development or exploring the role of KRT31 in disease pathogenesis, this antibody is essential for researchers in the fields of dermatology, oncology, and beyond.
| Antibody Name: | KRT31 Antibody (PACO14065) |
| Antibody SKU: | PACO14065 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human KRT31 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO14065(KRT31 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
 | Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane: A549 cells, Primary antibody: PACO14065(KRT31 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO14065(KRT31 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acid, c protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. |
| Synonyms: | Keratin-31 |
| UniProt Protein Function: | KRT31: is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cytoskeletal Chromosomal Location of Human Ortholog: 17q21.2 Cellular Component: extracellular space; intermediate filament Molecular Function:structural constituent of cytoskeleton Biological Process: epidermis development |
| NCBI Summary: | The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q15323 |
| NCBI GenInfo Identifier: | 209572740 |
| NCBI Gene ID: | 3881 |
| NCBI Accession: | Q15323.3 |
| UniProt Secondary Accession: | Q15323,O76009, Q14525, O76011, |
| UniProt Related Accession: | Q15323 |
| Molecular Weight: | 416 |
| NCBI Full Name: | Keratin, type I cuticular Ha1 |
| NCBI Synonym Full Names: | keratin 31 |
| NCBI Official Symbol: | KRT31Â Â |
| NCBI Official Synonym Symbols: | HA1; Ha-1; hHa1; KRTHA1Â Â |
| NCBI Protein Information: | keratin, type I cuticular Ha1; K31; keratin-31; hard keratin, type I, 1; keratin, hair, acidic,1; hair keratin, type I Ha1 |
| UniProt Protein Name: | Keratin, type I cuticular Ha1 |
| UniProt Synonym Protein Names: | Hair keratin, type I Ha1; Keratin-31; K31 |
| UniProt Gene Name: | KRT31Â Â |
| UniProt Entry Name: | K1H1_HUMAN |
Related Products
KRT31 Antibody (PACO14066)
