The KRT20 Polyclonal Antibody (CAB0248) is a valuable tool for researchers studying the keratin 20 protein. Keratin 20 is a type I keratin protein that is expressed in epithelial cells, particularly in the gastrointestinal tract.This polyclonal antibody is produced in rabbits and is highly reactive with human samples. It has been validated for use in various applications, including Western blot, immunohistochemistry, and immunofluorescence. By binding specifically to the KRT20 protein, this antibody enables researchers to detect and analyze the expression of KRT20 in different cell types and tissues.The KRT20 Polyclonal Antibody is particularly useful for studies in cancer research, as aberrant expression of keratins has been observed in various types of cancers.
By understanding the role of KRT20 in cancer development and progression, researchers may uncover new insights into potential diagnostic and therapeutic strategies.In conclusion, the KRT20 Polyclonal Antibody (CAB0248) is a reliable tool for researchers interested in investigating the functional significance of keratin 20 in normal physiology and disease. Its versatility in various applications makes it an essential component for studies in cancer biology and other fields related to epithelial cell biology.
Product Name:
Cytokeratin 20 (KRT20) Rabbit Polyclonal Antibody
SKU:
CAB0248
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 245-424 of human Cytokeratin 20 (Cytokeratin 20 (KRT20)) (NP_061883.1).
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.
Purification Method:
Affinity purification
Gene ID:
54474
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Confocal immunofluorescence analysis of A-431 cells using Cytokeratin 20 (Cytokeratin 20 (KRT20)) antibody (CAB0248) at dilution of 1:200. Blue: DAPI for nuclear staining.
