The KRT17 Polyclonal Antibody (CAB2175) is a valuable tool for researchers studying the keratin 17 protein, an important cytoskeletal protein known for its involvement in cell migration and wound healing processes. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.Keratin 17, a type I keratin protein, is expressed in various epithelial tissues and is particularly important in hair follicle formation and regeneration.
Dysregulation of KRT17 has been linked to various skin disorders and cancers, making it a target of interest for dermatology and oncology research. By using the KRT17 Polyclonal Antibody, researchers can detect and analyze the expression levels of KRT17 in different cell types, providing valuable insights into its role in both normal and pathological conditions.
Product Name:
Cytokeratin 17 (KRT17) Rabbit Polyclonal Antibody
SKU:
CAB2175
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 133-432 of human Cytokeratin 17 (Cytokeratin 17 (KRT17)) (NP_000413.1).
This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex.
Purification Method:
Affinity purification
Gene ID:
3872
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Cytokeratin 17 (Cytokeratin 17 (KRT17)) antibody (CAB2175) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
