null

KRT17 Monoclonal Antibody [PAT9F3AT] (CPAB0628)

SKU:
CPAB0628
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT9F3AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

KRT17 Monoclonal Antibody [PAT9F3AT] (CPAB0628)

The KRT17 Polyclonal Antibody (CPAB0628) is a valuable tool for researchers studying Keratin 17 (KRT17), a protein involved in the structural integrity of epithelial cells. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.KRT17 is a type I keratin protein that is typically found in hair follicles, nails, and certain glands. Aberrant expression of KRT17 has been linked to various diseases, including cancer and skin disorders. By using the KRT17 Polyclonal Antibody, researchers can detect and analyze the expression of KRT17 in different cell types, providing valuable insights into its role in normal physiology and disease pathology.

This antibody is an essential tool for studies in dermatology, oncology, and cell biology, allowing researchers to further explore the functions of KRT17 and its potential as a therapeutic target. By understanding the mechanisms underlying KRT17 regulation and expression, new treatment strategies may be developed for conditions associated with KRT17 dysregulation.

Product Name:KRT17 Antibody
Product Sku:CPAB0628
Size:5μg
Host Species:Mouse
Immunogen:Anti-human KRT17 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human KRT17 protein 1-432 amino acids purified from Ecoli.
Clone:PAT9F3AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:KRT17 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2a
Background:Cytokeratin 17 also known as KRT17 is a type I cytokeratin. KRT17 is found in nail beds, hair follicles, sebaceous glands, and other epidermal appendages. Mutations in KRT17 lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. KRT17 takes part in the formation and maintenance of a variety of skin appendages, particularly in determining shape and orientation of hair. KRT17 also modulates the function of TNF-alpha in the precise context of hair cycling. Moreover, KRT17 regulates protein synthesis and epithelial cell growth all through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway.
Synonyms:Keratin 17, PCHC1, 39.1, CK-17, K17, PC2, PC, cytokeratin-17, Keratin 17 Epitope S1, Keratin 17 Epitope S2, Keratin 17 Epitope S4, Keratin, Type I Cytoskeletal 1, keratin-17, Cytokeratin-17, Keratin-17.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Related Products