KRT14 Monoclonal Antibody [PAT13F4AT] (CPAB0627)
- SKU:
- CPAB0627
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- PAT13F4AT
- Applications:
- WB
- ELISA
Description
KRT14 Monoclonal Antibody [PAT13F4AT] (CPAB0627)
The KRT14 Polyclonal Antibody (CPAB0627) is a valuable tool for research involving Keratin 14 (KRT14), a protein expressed in epithelial cells, particularly those of the skin and hair follicles. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to KRT14, researchers can detect and analyze the protein in various cell types, making it ideal for studies in dermatology, oncology, and regenerative medicine.
KRT14 is a marker of epithelial cells undergoing active cell division and differentiation, making it a useful indicator of tissue regeneration and repair. Its role in maintaining the structural integrity of epithelial tissues also makes it relevant to studies on skin disorders, wound healing, and cancer development. By understanding the function and regulation of KRT14, researchers can uncover new insights into epithelial biology and potentially develop novel treatments for related diseases.
Product Name: | KRT14 Antibody |
Product Sku: | CPAB0627 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human KRT14 mAb, clone PAT13F4AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human KRT14 protein 1-472 amino acids purified from Ecoli. |
Clone: | PAT13F4AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA |
Purification Method: | KRT14 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG2a |
Background: | Cytokeratin 14 is a member of the keratin family, the most diverse group of intermediate filaments. Cytokeratin 14 is a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. |
Synonyms: | Keratin, type I cytoskeletal 14, Cytokeratin-14, CK-14, Keratin-14, K14, KRT14, NFJ, CK14, EBS3, EBS4. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |