Cytokeratin 13 (KRT13) Rabbit Polyclonal Antibody (CAB7697)
- SKU:
- CAB7697
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | Cytokeratin 13 (KRT13) Rabbit Polyclonal Antibody |
SKU: | CAB7697 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 269-458 of human Cytokeratin 13 (Cytokeratin 13 (KRT13)) (NP_705694.2). |
Sequence: | DLTR VLAE MREQ YEAM AERN RRDA EEWF HAKS AELN KEVS TNTA MIQT SKTE ITEL RRTL QGLE IELQ SQLS MKAG LENT VAET ECRY ALQL QQIQ GLIS SIEA QLSE LRSE MECQ NQEY KMLL DIKT RLEQ EIAT YRSL LEGQ DAKM IGFP SSAG SVSP RSTS VTTT SSAS VTTT SNAS GRRT SDVR RP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | K13; CK13; WSN2; Cytokeratin 13 (KRT13) |
Positive Sample: | MCF7,Mouse intestine,Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | cytoskeleton, cytosol, extracellular exosome, intermediate filament cytoskeleton, nucleus |
Calculated MW: | 50kDa |
Observed MW: | 50kDa |
The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described.
Purification Method: | Affinity purification |
Gene ID: | 3860 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |