The Anti-Cytokeratin 13 (KRT13) Antibody (CAB0411) is a valuable tool for researchers studying cytokeratin 13, a protein that is involved in maintaining the structural integrity of epithelial cells. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it a reliable choice for immunohistochemistry and immunofluorescence applications.Cytokeratin 13 is a member of the cytokeratin family, which are intermediate filament proteins found in epithelial cells. It is particularly expressed in certain types of epithelial tissues, such as the oral mucosa and esophageal epithelium. The expression of cytokeratin 13 can be altered in various disease states, including cancer, making it a useful biomarker for diagnostic and research purposes.
By using the Anti-Cytokeratin 13 (KRT13) Antibody (CAB0411), researchers can further explore the role of cytokeratin 13 in normal physiological processes and disease pathology. This antibody enables the detection and visualization of cytokeratin 13 in tissue samples, providing valuable insights into its localization and function. Overall, this antibody is an essential tool for advancing our understanding of cytokeratin 13 biology and its implications in health and disease.
Product Name:
Cytokeratin 13 (KRT13) Rabbit Monoclonal Antibody
SKU:
CAB0411
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Cytokeratin 13 (KRT13) (P13646).
Sequence:
LTGN EKIT MQNL NDRL ASYL EKVR ALEE ANAD LEVK IRDW HLKQ SPAS PERD YSPY YKTI EELR DKIL TATI ENNR VILE IDNA RLAA DDFR LKYE NELA L
The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described.
Purification Method:
Affinity purification
Gene ID:
3860
Clone Number:
ARC1824
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Cytokeratin 13 (KRT13) (KRT13) Rabbit mAb (CAB0411) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
