The KRT10 Polyclonal Antibody (CAB7908) is an essential tool for researchers studying keratin 10, a key structural protein found in epithelial cells, particularly in the skin. This polyclonal antibody, produced using rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting.Keratin 10 plays a crucial role in maintaining the structural integrity of the skin and other epithelial tissues, making it a valuable target for research in dermatology, wound healing, and cancer biology. By specifically binding to keratin 10, this antibody allows for the accurate detection and analysis of the protein in different cell types, enabling researchers to delve deeper into its functions and implications in various biological processes.
With its ability to target keratin 10, the KRT10 Polyclonal Antibody is an invaluable tool for investigating skin disorders, epithelial cell biology, and other related fields. Its reliability and specificity make it an excellent choice for researchers looking to expand their understanding of keratin 10 and its role in health and disease.
Product Name:
KRT10 Rabbit Polyclonal Antibody
SKU:
CAB7908
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 350-460 of human KRT10 (NP_000412.3).
This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21.
Purification Method:
Affinity purification
Gene ID:
3858
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of MCF7 cells, using KRT10 antibody (CAB7908) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
