KREMEN2 Rabbit Polyclonal Antibody (CAB16202)
- SKU:
- CAB16202
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | KREMEN2 Rabbit Polyclonal Antibody |
SKU: | CAB16202 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-360 of human KREMEN2 (NP_078783.1). |
Sequence: | GQLC GGDG RLGV YEVS VGSC QGNW TAPQ GVIY SPDF PDEY GPDR NCSW ALGP PGAA LELT FRLF ELAD PRDR LELR DAAS GSLL RAFD GARP PPSG PLRL GTAA LLLT FRSD ARGH AQGF ALTY RGLQ DAAE DPEA PEGS AQTP AAPL DGAN VSCS PRPG A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | KRM2; KREMEN2 |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | plasma membrane |
Calculated MW: | 49kDa |
Observed MW: | 48kDa |
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 79412 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |