KREMEN1 Rabbit Polyclonal Antibody (CAB10507)
- SKU:
- CAB10507
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | KREMEN1 Rabbit Polyclonal Antibody |
SKU: | CAB10507 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-380 of human KREMEN1 (NP_001034659.2). |
Sequence: | YGEA ASTE CNSV CFGD HTQP CGGD GRII LFDT LVGA CGGN YSAM SSVV YSPD FPDT YATG RVCY WTIR VPGA SHIH FSFP LFDI RDSA DMVE LLDG YTHR VLAR FHGR SRPP LSFN VSLD FVIL YFFS DRIN QAQG FAVL YQAV KEEL PQER PAVN QTVA EVIT EQAN LSVS AARS SKVL YVIT TSPS HPPQ TVPG WTVY G |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | KRM1; ECTD13; KREMEN; KREMEN1 |
Positive Sample: | A-549,22Rv1,A375,Mouse lung,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 52kDa |
Observed MW: | 70kDa |
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Mutations in this gene result in ectodermal dysplasia. This protein has also been found to be a functional receptor for Coxsackievirus A10 and may be an alternative entry receptor for SARS-CoV-2.
Purification Method: | Affinity purification |
Gene ID: | 83999 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |