[KO Validated] KRAS Rabbit Polyclonal Antibody (CAB12704)
- SKU:
- CAB12704
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] KRAS Rabbit Polyclonal Antibody |
SKU: | CAB12704 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-188 of human KRAS (NP_203524.1). |
Sequence: | DEYD PTIE DSYR KQVV IDGE TCLL DILD TAGQ EEYS AMRD QYMR TGEG FLCV FAIN NTKS FEDI HHYR EQIK RVKD SEDV PMVL VGNK CDLP SRTV DTKQ AQDL ARSY GIPF IETS AKTR QRVE DAFY TLVR EIRQ YRLK KISK EEKT PGCV KIKK CII |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IF/ICC,1:50 - 1:200 |
Synonyms: | NS; NS3; OES; CFC2; RALD; K-Ras; KRAS1; KRAS2; RASK2; KI-RAS; C-K-RAS; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-Ras 2; 'C-K-RAS; c-Ki-ras; c-Ki-ras2; AS |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Cytoplasmic side, Lipid-anchor, cytosol. |
Calculated MW: | 22kDa |
Observed MW: | 21kDa |
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
Purification Method: | Affinity purification |
Gene ID: | 3845 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |