KRAS+HRAS+NRAS Rabbit Monoclonal Antibody (CAB19779)
- SKU:
- CAB19779
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | KRAS+HRAS+NRAS Rabbit Monoclonal Antibody |
SKU: | CAB19779 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-188 of human NRAS (P01111). |
Sequence: | MTEY KLVV VGAG GVGK SALT IQLI QNHF VDEY DPTI EDSY RKQV VIDG ETCL LDIL DTAG QEEY SAMR DQYM RTGE GFLC VFAI NNSK SFAD INLY REQI KRVK DSDD VPMV LVGN KCDL PTRT VDTK QAHE LAKS YGIP FIET SAKT RQGV EDAF YTLV REIR QYRM KKLN SSDD GTQG CMGL PCVV |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KI-RAS; KRAS1; KRAS2; NS; NS3; RALD; RASK2; c-Ki-ras2; KRAS+HRAS+NRAS |
Positive Sample: | HT-29,293T,MCF7,NIH/3T3,C6,Mouse lung,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, extracellular exosome, Golgi apparatus, plasma membrane |
Calculated MW: | 21kDa |
Observed MW: | 21kDa |
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
Purification Method: | Affinity purification |
Gene ID: | 4893/3265/3845 |
Clone Number: | ARC2369 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |